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Truncating PKHD1 and PKD2 mutations alter energy metabolism

Deficiency in polycystin 1 triggers specific changes in energy metabolism. To determine whether defects in other human cystoproteins have similar effects, we studied extracellular acidification and glucose metabolism in human embryonic kidney (HEK-293) cell lines with polycystic kidney and hepatic d...

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Podrobná bibliografie
Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Chumley, Phillip, Zhou, Juling, Mrug, Sylvie, Chacko, Balu, Parant, John M., Challa, Anil K., Wilson, Landon S., Berryhill, Taylor F., Barnes, Stephen, Kesterson, Robert A., Bell, P. Darwin, Darley-Usmar, Victor M., Yoder, Bradley K., Mrug, Michal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442375/
https://ncbi.nlm.nih.gov/pubmed/30566001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00167.2018
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