Mass Spectrometry-based Absolute Quantification of 20S Proteasome Status for Controlled Ex-vivo Expansion of Human Adipose-derived Mesenchymal Stromal/Stem Cells

The proteasome controls a multitude of cellular processes through protein degradation and has been identified as a therapeutic target in oncology. However, our understanding of its function and the development of specific modulators are hampered by the lack of a straightforward method to determine t...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Menneteau, Thomas, Fabre, Bertrand, Garrigues, Luc, Stella, Alexandre, Zivkovic, Dusan, Roux-Dalvai, Florence, Mouton-Barbosa, Emmanuelle, Beau, Mathilde, Renoud, Marie-Laure, Amalric, François, Sensébé, Luc, Gonzalez-de-Peredo, Anne, Ader, Isabelle, Burlet-Schiltz, Odile, Bousquet, Marie-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442357/
https://ncbi.nlm.nih.gov/pubmed/30700495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000958
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