Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression

BACKGROUND: c-Src is a driver oncogene well-known for tumorigenic signaling, but little for metabolic function. Previous reports about c-Src regulation of glucose metabolism prompted us to investigate its function in other nutrient modulation, particularly in lipid metabolism. METHODS: Oil-red O sta...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Hua, Tuyen N.M., Kim, Min-Kyu, Vo, Vu T.A., Choi, Jong-Whan, Choi, Jang Hyun, Kim, Hyun-Won, Cha, Seung-Kuy, Park, Kyu-Sang, Jeong, Yangsik
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442332/
https://ncbi.nlm.nih.gov/pubmed/30755372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.02.015
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