pH and reduction dual-responsive micelles based on novel polyurethanes with detachable poly(2-ethyl-2-oxazoline) shell for controlled release of doxorubicin

We describe a biodegradable amphiphilic polyurethane (PU) with disulfide bonds in the main chain [PEtOz-b-PU(SS)-b-PEtOz]. This multi-block PU was synthesized using poly (ε-caprolactone) diol (PCL-SS-PCL) and poly (2-ethyl-2-oxazoline) (PEtOz-OH) as soft segments, and bis (2-isocyanatoethyl) disulfi...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Drug Deliv
Hoofdauteurs: Bu, Leran, Zhang, Hena, Xu, Kang, Du, Baixiang, Zhu, Caihong, Li, Yuling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442156/
https://ncbi.nlm.nih.gov/pubmed/30895837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1580323
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items