MicroRNA-144-3p targets relaxin/insulin-like family peptide receptor 1 (RXFP1) expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis

The hormone relaxin is considered a potential therapy for idiopathic pulmonary fibrosis (IPF). We have previously shown that a potential limitation to relaxin-based IPF therapy is decreased expression of a relaxin receptor, relaxin/insulin-like family peptide receptor 1 (RXFP1), in IPF fibroblasts....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bahudhanapati, Harinath, Tan, Jiangning, Dutta, Justin A., Strock, Stephen B., Sembrat, John, Àlvarez, Diana, Rojas, Mauricio, Jäger, Benedikt, Prasse, Antje, Zhang, Yingze, Kass, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442041/
https://ncbi.nlm.nih.gov/pubmed/30709904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004910
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