Application of pharmacokinetic/pharmacodynamic analysis to evaluate the adequacy of antimicrobial therapy for pediatric acute otitis media in Spain before and after the introduction of the PCV7 vaccine

OBJECTIVES: To evaluate, by applying pharmacokinetic/pharmacodynamic (PK/PD) analysis, if the change in antibiotic susceptibility after the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in Spain had any influence on the usefulness of the antimicrobials more frequently used as em...

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Publicado en:Rev Esp Quimioter
Autores principales: Ibar-Bariain, Maitane, Rodríguez-Gascón, Alicia, Isla, Arantxa, Solinís, María Ángeles, Canut-Blasco, Andrés
Formato: Artigo
Lenguaje:Inglês
Publicado: Sociedad Española de Quimioterapia 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441979/
https://ncbi.nlm.nih.gov/pubmed/30727714
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