Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways

BACKGROUND: We and others have shown that dipeptidyl peptidase-IV (DPP4) expression is increased in obesity/atherosclerosis and is positively correlated with atherosclerotic burden. However, the mechanism by which DPP4 expression is regulated in obesity remains unclear. In this study, we investigate...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Rao, Xiaoquan, Zhao, Shi, Braunstein, Zachary, Mao, Hong, Razavi, Michael, Duan, Lihua, Wei, Yingying, Toomey, Amelia C., Rajagopalan, Sanjay, Zhong, Jixin
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Research paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441950/
https://ncbi.nlm.nih.gov/pubmed/30738832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.065
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