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Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma
Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with limited response to cytotoxic chemoradiotherapy, as well as newer immunotherapies. The PDA tumor microenvironment contains infiltrating immune cells including cytotoxic T cells; however, there is an overall immunosuppressive milieu. Hyp...
Gespeichert in:
| Veröffentlicht in: | Clin Transl Med |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6441665/ https://ncbi.nlm.nih.gov/pubmed/30931508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-019-0226-9 |
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