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Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with limited response to cytotoxic chemoradiotherapy, as well as newer immunotherapies. The PDA tumor microenvironment contains infiltrating immune cells including cytotoxic T cells; however, there is an overall immunosuppressive milieu. Hyp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Transl Med
Prif Awduron: Daniel, S. K., Sullivan, K. M., Labadie, K. P., Pillarisetty, V. G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441665/
https://ncbi.nlm.nih.gov/pubmed/30931508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-019-0226-9
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