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Mitochondrial Damage and Drp1 Overexpression in Rifampicin- and Isoniazid-induced Liver Injury Cell Model

Background and Aims: Rifampicin (RFP) and isoniazid (INH) are widely used as anti-tuberculosis agents. However, the mechanisms underlying the involvement of reactive oxygen species and mitochondria in RFP- and INH-related hepatotoxicity have not been established yet. This study aimed to observe the...

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Detalhes bibliográficos
Publicado no:J Clin Transl Hepatol
Main Authors: Li, Fangfang, Zhou, Juan, Li, Yi, Sun, Kewei, Chen, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: XIA & HE Publishing Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441640/
https://ncbi.nlm.nih.gov/pubmed/30944818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14218/JCTH.2018.00052
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