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MDM2 promotes epithelial–mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinoma
BACKGROUND: Mouse double minute 2 (MDM2) contributes to cancer metastasis and epithelial–mesenchymal transition (EMT). This study aimed to investigate small mothers against decapentaplegic (Smad) signaling in MDM2-mediated EMT in lung adenocarcinoma (LAC). MATERIALS AND METHODS: Expression patterns...
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| Publicado no: | Onco Targets Ther |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6441555/ https://ncbi.nlm.nih.gov/pubmed/30988629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S185076 |
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