A genome-wide study of DNA methylation in nasal epithelium and atopy and atopic asthma in children

BACKGROUND: Epigenetic mechanisms may alter the airway epithelial barrier and ultimately lead to atopic diseases such as asthma. Here we aim to identify DNA methylation profiles that are associated with -and accurately classify- atopy and atopic asthma in school-aged children. METHODS: We conducted...

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Vydáno v:Lancet Respir Med
Hlavní autoři: Forno, Erick, Wang, Ting, Qi, Cancan, Yan, Qi, Xu, Cheng-Jian, Boutaoui, Nadia, Han, Yueh Ying, Weeks, Daniel E., Jiang, Yale, Rosser, Franziska, Vonk, Judith M., Brouwer, Sharon, Acosta-Perez, Edna, Colón-Semidey, Angel, Alvarez, María, Canino, Glorisa, Koppelman, Gerard H., Chen, Wei, Celedón, Juan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441380/
https://ncbi.nlm.nih.gov/pubmed/30584054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(18)30466-1
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