Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome

BACKGROUND: Patients diagnosed with chronic fatigue syndrome (CFS) or fibromyalgia experience chronic pain. Concomitantly, the rat model of CFS exhibits microglial activation in the lumbar spinal cord and pain behavior without peripheral tissue damage and/or inflammation. The present study addressed...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Yasui, Masaya, Menjyo, Yuki, Tokizane, Kyohei, Shiozawa, Akiko, Tsuda, Makoto, Inoue, Kazuhide, Kiyama, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441145/
https://ncbi.nlm.nih.gov/pubmed/30927920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1456-x
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