Venlafaxine ER Blocks the Norepinephrine Transporter in the Brain of Patients with Major Depressive Disorder: a PET Study Using [(18)F]FMeNER-D(2)

BACKGROUND: The in vivo binding of clinical dose of venlafaxine on norepinephrine transporter has been questioned because venlafaxine has higher in vitro affinity to serotonin transporter than that to norepinephrine transporter. Although serotonin transporter occupancy of clinically relevant doses o...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Arakawa, Ryosuke, Stenkrona, Per, Takano, Akihiro, Svensson, Jonas, Andersson, Max, Nag, Sangram, Asami, Yuko, Hirano, Yoko, Halldin, Christer, Lundberg, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Regular Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441126/
https://ncbi.nlm.nih.gov/pubmed/30649319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyz003
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