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Multiplex imaging relates quantal glutamate release to presynaptic Ca(2+) homeostasis at multiple synapses in situ

Information processing by brain circuits depends on Ca(2+)-dependent, stochastic release of the excitatory neurotransmitter glutamate. Whilst optical glutamate sensors have enabled detection of synaptic discharges, understanding presynaptic machinery requires simultaneous readout of glutamate releas...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Jensen, Thomas P., Zheng, Kaiyu, Cole, Nicholas, Marvin, Jonathan S., Looger, Loren L., Rusakov, Dmitri A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441074/
https://ncbi.nlm.nih.gov/pubmed/30926781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09216-8
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