Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma

Emerging evidence reveals enrichment of glioma-initiating cells (GICs) following therapeutic intervention. One factor known to contribute to this enrichment is cellular plasticity—the ability of glioma cells to attain multiple phenotypes. To elucidate the molecular mechanisms governing therapy-induc...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hasan, Tanwir, Caragher, Seamus P., Shireman, Jack M., Park, Cheol H., Atashi, Fatemeh, Baisiwala, Shivani, Lee, Gina, Guo, Donna, Wang, Jennifer Y., Dey, Mahua, Wu, Meijing, Lesniak, Maciej S., Horbinski, Craig M., James, C. David, Ahmed, Atique U.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441047/
https://ncbi.nlm.nih.gov/pubmed/30926789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1387-6
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