Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies

The increasing global prevalence of human immunodeficiency virus (HIV) is estimated at 36.7 million people currently infected. Lifelong antiretroviral (ARV) drug combination dosing allows management as a chronic condition by suppressing circulating viral load to allow for a near-normal life; however...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Hobson, James J., Al-khouja, Amer, Curley, Paul, Meyers, David, Flexner, Charles, Siccardi, Marco, Owen, Andrew, Meyers, Caren Freel, Rannard, Steve P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441007/
https://ncbi.nlm.nih.gov/pubmed/30926773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09354-z
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