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Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase

RAD51 assembly on single-stranded (ss)DNAs is a crucial step in the homology-dependent repair of DNA damage for genomic stability. The formation of the RAD51 filament is promoted by various RAD51-interacting proteins including RAD51 paralogues. However, the mechanisms underlying the differential con...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Matsuzaki, Kenichiro, Kondo, Shizuka, Ishikawa, Tatsuya, Shinohara, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440994/
https://ncbi.nlm.nih.gov/pubmed/30926776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09190-1
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