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Quantitative relationships between SMAD dynamics and target gene activation kinetics in single live cells

The transduction of extracellular signals through signaling pathways that culminate in a transcriptional response is central to many biological processes. However, quantitative relationships between activities of signaling pathway components and transcriptional output of target genes remain poorly e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tidin, Onur, Friman, Elias T., Naef, Felix, Suter, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440972/
https://ncbi.nlm.nih.gov/pubmed/30926874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41870-2
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