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IL-6 Induced by Social Stress Promotes a Unique Transcriptional Signature in the Monocytes that Facilitate Anxiety

BACKGROUND: Interleukin (IL)-6 is elevated in circulation with chronic stress and may contribute to neurobehavioral complications. We have reported that repeated social defeat (RSD) stress in mice caused recruitment of proinflammatory monocytes to the brain and triggered the onset of anxiety-like be...

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Bibliografski detalji
Izdano u:Biol Psychiatry
Glavni autori: Niraula, Anzela, Witcher, Kristina G., Sheridan, John F., Godbout, Jonathan P.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440848/
https://ncbi.nlm.nih.gov/pubmed/30447911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.09.030
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