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IL-6 Induced by Social Stress Promotes a Unique Transcriptional Signature in the Monocytes that Facilitate Anxiety

BACKGROUND: Interleukin (IL)-6 is elevated in circulation with chronic stress and may contribute to neurobehavioral complications. We have reported that repeated social defeat (RSD) stress in mice caused recruitment of proinflammatory monocytes to the brain and triggered the onset of anxiety-like be...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Niraula, Anzela, Witcher, Kristina G., Sheridan, John F., Godbout, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440848/
https://ncbi.nlm.nih.gov/pubmed/30447911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.09.030
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