The Influence of Microglial Elimination and Repopulation on Stress-Sensitization Induced by Repeated Social Defeat

BACKGROUND: Stress is associated with an increased prevalence of anxiety and depression. Repeated social defeat (RSD) stress in mice increases the release of monocytes from the bone marrow that are recruited to the brain by microglia. These monocytes enhance inflammatory signaling and augment anxiet...

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Veröffentlicht in:Biol Psychiatry
Hauptverfasser: Weber, Michael D., McKim, Daniel B., Niraula, Anzela, Witcher, Kristina G., Yin, Wenyuan, Sobol, Carly G, Wang, Yufen, Sawicki, Caroline M., Sheridan, John F, Godbout, Jonathan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440809/
https://ncbi.nlm.nih.gov/pubmed/30527629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.10.009
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