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Optimal parameter identification of synthetic gene networks using harmony search algorithm

Computational modeling of engineered gene circuits is an important while challenged task in systems biology. In order to describe and predict the response behaviors of genetic circuits using reliable model parameters, this paper applies an optimal experimental design(OED) method to obtain input sign...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Zhang, Wei, Li, Wenchao, Zhang, Jianming, Wang, Ning
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440652/
https://ncbi.nlm.nih.gov/pubmed/30925150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213977
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