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How a circularized tmRNA moves through the ribosome
During trans-translation, transfer-messenger RNA (tmRNA) and small protein B (SmpB), together rescue ribosomes stalled on a truncated mRNA, and tag the nascent polypeptide for degradation. We used electron cryo-microscopy to determine structures of three key states of the tmRNA-SmpB-ribosome complex...
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| 出版年: | Science |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6440651/ https://ncbi.nlm.nih.gov/pubmed/30765567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav9370 |
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