Early Stage Alterations in White Matter and Decreased Functional Interhemispheric Hippocampal Connectivity in the 3xTg Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized in the late stages by amyloid-β (Aβ) plaques and neurofibrillary tangles. Nevertheless, recent evidence has indicated that early changes in cerebral connectivity could compromise cognitive functions even before the appearance of the classical neuropathologic...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Manno, Francis A. M., Isla, Arturo G., Manno, Sinai H. C., Ahmed, Irfan, Cheng, Shuk Han, Barrios, Fernando A., Lau, Condon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440287/
https://ncbi.nlm.nih.gov/pubmed/30967770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00039
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