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Molecular basis of the anti-hyperglycemic activity of RA-3 in hyperlipidemic and streptozotocin-induced type 2 diabetes in rats

BACKGROUND: Insulin resistance is a hallmark of type 2 diabetes mellitus (T2DM) and the underlying cause of various metabolic changes observed in type 2 diabetic patients. This study investigated the molecular basis of the anti-hyperglycemic activity of the lanosteryl triterpene (RA-3), from Protorh...

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Publicat a:Diabetol Metab Syndr
Autors principals: Mabhida, Sihle Ephraim, Johnson, Rabia, Ndlovu, Musawenkosi, Louw, Johan, Opoku, Andrew, Mosa, Rebamang Anthony
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440151/
https://ncbi.nlm.nih.gov/pubmed/30976328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-019-0424-z
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