Increased expression of cancer-associated fibroblast markers at the invasive front and its association with tumor-stroma ratio in colorectal cancer

BACKGROUND: The tumor microenvironment has a critical role in regulating cancer cell behavior. Tumors with high stromal content are associated with poor patient outcome. The tumor-stroma ratio (TSR) identifies colorectal cancers (CRC) with poor patient prognosis based on hematoxylin & eosin stai...

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Publicat a:BMC Cancer
Autors principals: Sandberg, Tessa P., Stuart, Maaike P. M. E., Oosting, Jan, Tollenaar, Rob A. E. M., Sier, Cornelis F. M., Mesker, Wilma E.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440123/
https://ncbi.nlm.nih.gov/pubmed/30922247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5462-2
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