Rechallenge for Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer With Acquired Resistance to First-line Cetuximab and Irinotecan: A Phase 2 Single-Arm Clinical Trial

IMPORTANCE: Based on a small retrospective study, rechallenge with cetuximab-based therapy for patients with KRAS wild-type metastatic colorectal cancer (mCRC) who were previously treated with the same anti–epidermal growth factor receptor–based regimen might be efficacious. Recent data suggest the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JAMA Oncol
मुख्य लेखकों: Cremolini, Chiara, Rossini, Daniele, Dell’Aquila, Emanuela, Lonardi, Sara, Conca, Elena, Del Re, Marzia, Busico, Adele, Pietrantonio, Filippo, Danesi, Romano, Aprile, Giuseppe, Tamburini, Emiliano, Barone, Carlo, Masi, Gianluca, Pantano, Francesco, Pucci, Francesca, Corsi, Domenico C., Pella, Nicoletta, Bergamo, Francesca, Rofi, Eleonora, Barbara, Cecilia, Falcone, Alfredo, Santini, Daniele
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Medical Association 2018
विषय:
Original Investigation
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439839/
https://ncbi.nlm.nih.gov/pubmed/30476968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.5080
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