Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer: Phase 1b Results From the JAVELIN Solid Tumor Trial

IMPORTANCE: Current treatment options for progressive ovarian cancer provide limited benefit, particularly in patients whose disease has become resistant to platinum-based chemotherapy. OBJECTIVE: To assess the efficacy and safety of avelumab, an anti–programmed death-ligand 1 agent, in a cohort of...

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Bibliografiske detaljer
Udgivet i:JAMA Oncol
Main Authors: Disis, Mary L., Taylor, Matthew H., Kelly, Karen, Beck, J. Thaddeus, Gordon, Michael, Moore, Kathleen M., Patel, Manish R., Chaves, Jorge, Park, Haeseong, Mita, Alain C., Hamilton, Erika P., Annunziata, Christina M., Grote, Hans Juergen, von Heydebreck, Anja, Grewal, Jaspreet, Chand, Vikram, Gulley, James L.
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2019
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439837/
https://ncbi.nlm.nih.gov/pubmed/30676622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.6258
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