Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer: Phase 1b Results From the JAVELIN Solid Tumor Trial

IMPORTANCE: Current treatment options for progressive ovarian cancer provide limited benefit, particularly in patients whose disease has become resistant to platinum-based chemotherapy. OBJECTIVE: To assess the efficacy and safety of avelumab, an anti–programmed death-ligand 1 agent, in a cohort of...

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發表在:JAMA Oncol
Main Authors: Disis, Mary L., Taylor, Matthew H., Kelly, Karen, Beck, J. Thaddeus, Gordon, Michael, Moore, Kathleen M., Patel, Manish R., Chaves, Jorge, Park, Haeseong, Mita, Alain C., Hamilton, Erika P., Annunziata, Christina M., Grote, Hans Juergen, von Heydebreck, Anja, Grewal, Jaspreet, Chand, Vikram, Gulley, James L.
格式: Artigo
語言:Inglês
出版: American Medical Association 2019
主題:
Original Investigation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439837/
https://ncbi.nlm.nih.gov/pubmed/30676622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.6258
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