Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial

IMPORTANCE: Dexamethasone initiated after the first week of life reduces the rate of death or bronchopulmonary dysplasia (BPD) but may cause long-term adverse effects in very preterm infants. Hydrocortisone is increasingly used as an alternative, but evidence supporting its efficacy and safety is la...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Onland, Wes, Cools, Filip, Kroon, Andre, Rademaker, Karin, Merkus, Maruschka P., Dijk, Peter H., van Straaten, Henrica L., Te Pas, Arjan B., Mohns, Thilo, Bruneel, Els, van Heijst, Arno F., Kramer, Boris W., Debeer, Anne, Zonnenberg, Inge, Marechal, Yoann, Blom, Henry, Plaskie, Katleen, Offringa, Martin, van Kaam, Anton H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439762/
https://ncbi.nlm.nih.gov/pubmed/30694322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.21443
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