Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial

IMPORTANCE: Postoperative delirium is common following cardiac surgery and may be affected by choice of analgesic and sedative. OBJECTIVE: To evaluate the effect of postoperative intravenous (IV) acetaminophen (paracetamol) vs placebo combined with IV propofol vs dexmedetomidine on postoperative del...

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Vydáno v:JAMA
Hlavní autoři: Subramaniam, Balachundhar, Shankar, Puja, Shaefi, Shahzad, Mueller, Ariel, O’Gara, Brian, Banner-Goodspeed, Valerie, Gallagher, Jackie, Gasangwa, Doris, Patxot, Melissa, Packiasabapathy, Senthil, Mathur, Pooja, Eikermann, Matthias, Talmor, Daniel, Marcantonio, Edward R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
Preliminary Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439609/
https://ncbi.nlm.nih.gov/pubmed/30778597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.0234
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