Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure–Guided Strategy vs an Empirical High PEEP-Fio(2) Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial

IMPORTANCE: Adjusting positive end-expiratory pressure (PEEP) to offset pleural pressure might attenuate lung injury and improve patient outcomes in acute respiratory distress syndrome (ARDS). OBJECTIVE: To determine whether PEEP titration guided by esophageal pressure (P(ES)), an estimate of pleura...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Beitler, Jeremy R., Sarge, Todd, Banner-Goodspeed, Valerie M., Gong, Michelle N., Cook, Deborah, Novack, Victor, Loring, Stephen H., Talmor, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439595/
https://ncbi.nlm.nih.gov/pubmed/30776290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.0555
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