Acetylcholine Inhibits Platelet Activation

Platelets are key mediators of thrombosis. Many agonists of platelet activation are known, but fewer endogenous inhibitors of platelets, such as prostacyclin and nitric oxide (NO), have been identified. Acetylcholinesterase inhibitors, such as donepezil, can cause bleeding in patients, but the under...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Bennett, John A., Ture, Sara K., Schmidt, Rachel A., Mastrangelo, Michael A., Cameron, Scott J., Terry, Lara E., Yule, David I., Morrell, Craig N., Lowenstein, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Drug Discovery and Translational Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439456/
https://ncbi.nlm.nih.gov/pubmed/30765424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.253583
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