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GLCCI1 rs37973 is associated with the response of adrenal hormone to inhaled corticosteroids in asthma

BACKGROUND: Previous studies have demonstrated that glucocorticoid-induced transcript 1 gene (GLCCI1) rs37973 mutant genotype is associated with poor inhaled corticosteroid (ICS) response in asthmatics. As human airway relaxation is regulated by circulation epinephrine, which can be enhanced by cort...

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Bibliographische Detailangaben
Veröffentlicht in:World Allergy Organ J
Hauptverfasser: Xun, Qiufen, Hu, Chengping, Li, Xiaozhao, Hu, Xinyue, Qin, Ling, He, Ruoxi, Lu, Rongli, Feng, Juntao
Format: Artigo
Sprache:Inglês
Veröffentlicht: World Allergy Organization 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439416/
https://ncbi.nlm.nih.gov/pubmed/30937140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.waojou.2019.100017
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