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Dual-targeting by CRISPR/Cas9 leads to efficient point mutagenesis but only rare targeted deletions in the rice genome

The present study investigated the efficiency of CRISPR/Cas9 in creating genomic deletions as the basis of its application in removing selection marker genes or the intergenic regions. Three loci, representing a transgene and two rice genes, were targeted at two sites each, in separate experiments,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:3 Biotech
मुख्य लेखकों: Pathak, Bhuvan, Zhao, Shan, Manoharan, Muthusamy, Srivastava, Vibha
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer International Publishing 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439133/
https://ncbi.nlm.nih.gov/pubmed/30944805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-019-1690-z
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