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Purinergic implication in amyotrophic lateral sclerosis—from pathological mechanisms to therapeutic perspectives

Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous disorder characterized by degeneration of upper motor neurons in the brainstem and lower motor neurons in the spinal cord. Multiple mechanisms of motor neuron injury have been implicated, including more than 20 different genetic facto...

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Detalhes bibliográficos
Publicado no:Purinergic Signal
Main Authors: Cieślak, M., Roszek, K., Wujak, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439052/
https://ncbi.nlm.nih.gov/pubmed/30430356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-018-9633-4
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