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Impact of the secretome of activated pancreatic stellate cells on growth and differentiation of pancreatic tumour cells

Pancreatic ductal adenocarcinoma (PDAC) exists in a complex desmoplastic microenvironment. As part of it, pancreatic stellate cells (PSCs) provide a fibrotic niche, stimulated by a dynamic communication between activated PSCs and tumour cells. Investigating how PSCs contribute to tumour development...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Marzoq, Aseel J., Mustafa, Shakhawan A., Heidrich, Luzia, Hoheisel, Jörg D., Alhamdani, Mohamed Saiel Saeed
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438963/
https://ncbi.nlm.nih.gov/pubmed/30923340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41740-x
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