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Blocking antibodies induced by peanut oral and sublingual immunotherapy suppress basophil activation and are associated with sustained unresponsiveness

BACKGROUND: Oral and sublingual immunotherapies for peanut allergy have demonstrated efficacy in small clinical trials, however, mechanisms and biomarkers correlating with clinical outcomes remain elusive. Previous studies have demonstrated a role for IgG in post-OIT plasma in the suppression of IgE...

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Bibliografiske detaljer
Udgivet i:Clin Exp Allergy
Main Authors: Orgel, Kelly, Burk, Caitlin, Smeekens, Johanna, Suber, Jada, Hardy, Lakeya, Guo, Rishu, Burks, A. Wesley, Kulis, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438743/
https://ncbi.nlm.nih.gov/pubmed/30383313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13305
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