First-in-class immune-modulating small molecule Icaritin in advanced hepatocellular carcinoma: preliminary results of safety, durable survival and immune biomarkers

BACKGROUND: With poor prognosis and limited treatment options for advanced hepatocellular carcinoma (HCC), development of novel therapeutic agents is urgently needed. This single-arm phase I study sought to assess the safety and preliminary efficacy of icaritin in human as a potential oral immunothe...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Fan, Ying, Li, Shu, Ding, Xiaoyan, Yue, Jian, Jiang, Jun, Zhao, Hong, Hao, Rui, Qiu, Weiliang, Liu, Kezhen, Li, Ying, Wang, Shengdian, Zheng, Limin, Ye, Bin, Meng, Kun, Xu, Binghe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437929/
https://ncbi.nlm.nih.gov/pubmed/30922248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5471-1
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