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Topconfects: a package for confident effect sizes in differential expression analysis provides a more biologically useful ranked gene list

Differential gene expression analysis may discover a set of genes too large to easily investigate, so a means of ranking genes by biological interest level is desired. p values are frequently abused for this purpose. As an alternative, we propose a method of ranking by confidence bounds on the log f...

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Vydáno v:Genome Biol
Hlavní autoři: Harrison, Paul F., Pattison, Andrew D., Powell, David R., Beilharz, Traude H.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437914/
https://ncbi.nlm.nih.gov/pubmed/30922379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1674-7
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