Design, synthesis and biological evaluation of chalcone analogues with novel dual antioxidant mechanisms as potential anti-ischemic stroke agents

Scavenging reactive oxygen species (ROS) by antioxidants is the important therapy to cerebral ischemia-reperfusion injury (CIRI) in stroke. The antioxidant with novel dual-antioxidant mechanism of directly scavenging ROS and indirectly through antioxidant pathway activation may be a promising CIRI t...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Wang, Jiabing, Huang, Lili, Cheng, Chanchan, Li, Ge, Xie, Jingwen, Shen, Mengya, Chen, Qian, Li, Wulan, He, Wenfei, Qiu, Peihong, Wu, Jianzhang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437665/
https://ncbi.nlm.nih.gov/pubmed/30972281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.01.003
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