Gintonin-mediated release of astrocytic vascular endothelial growth factor protects cortical astrocytes from hypoxia-induced cell damages

BACKGROUND: Gintonin is a ginseng-derived exogenous ligand of the G protein-coupled lysophosphatidic acid (LPA) receptor. We previously reported that gintonin stimulates gliotransmitter release in primary cortical astrocytes. Astrocytes play key roles in the functions of neurovascular systems. Altho...

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Udgivet i:J Ginseng Res
Main Authors: Choi, Sun-Hye, Kim, Hyeon-Joong, Cho, Hee-Jung, Park, Sang-Deuk, Lee, Na-Eun, Hwang, Sung-Hee, Rhim, Hyewon, Kim, Hyoung-Chun, Cho, Ik-Hyun, Nah, Seung-Yeol
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437663/
https://ncbi.nlm.nih.gov/pubmed/30976168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgr.2018.05.006
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