LSD1 inhibition suppresses the growth of clear cell renal cell carcinoma via upregulating P21 signaling

Histone lysine-specific demethylase 1 (LSD1) has been implicated in the disease progression of several types of solid tumors. This study provides the first evidence showing that LSD1 overexpression occurred in 62.6% (224/358) of clear cell renal cell carcinomas (ccRCC). LSD1 expression was associate...

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Bibliografiske detaljer
Udgivet i:Acta Pharm Sin B
Main Authors: Zhu, Liangsong, Wang, Jianfeng, Kong, Wen, Huang, Jiwei, Dong, Baijun, Huang, Yiran, Xue, Wei, Zhang, Jin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
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Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437640/
https://ncbi.nlm.nih.gov/pubmed/30972280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.10.006
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