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An Optogenetic Kindling Model of Neocortical Epilepsy

Epileptogenesis is the gradual process by which the healthy brain develops epilepsy. However, the neuronal circuit changes that underlie epileptogenesis are not well understood. Unfortunately, current chemically or electrically induced epilepsy models suffer from lack of cell specificity, so it is s...

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Publicat a:Sci Rep
Autors principals: Cela, Elvis, McFarlan, Amanda R., Chung, Andrew J., Wang, Taiji, Chierzi, Sabrina, Murai, Keith K., Sjöström, P. Jesper
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437216/
https://ncbi.nlm.nih.gov/pubmed/30918286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41533-2
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