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Parent of origin genetic effects on methylation in humans are common and influence complex trait variation
Parent-of-origin effects (POE) exist when there is differential expression of alleles inherited from the two parents. A genome-wide scan for POE on DNA methylation at 639,238 CpGs in 5,101 individuals identifies 733 independent methylation CpGs potentially influenced by POE at a false discovery rate...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437195/ https://ncbi.nlm.nih.gov/pubmed/30918249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09301-y |
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