Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A

Inhibitors of the secretion of cancer exosomes, which promote cancer progression and metastasis, may not only accelerate exosome biology research but also offer therapeutic benefits for cancer patients. Here we identify sulfisoxazole (SFX) as an inhibitor of small extracellular vesicles (sEV) secret...

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Published in:Nat Commun
Main Authors: Im, Eun-Ju, Lee, Chan-Hyeong, Moon, Pyong-Gon, Rangaswamy, Gunassekaran Gowri, Lee, Byungheon, Lee, Jae Man, Lee, Jae-Chul, Jee, Jun-Goo, Bae, Jong-Sup, Kwon, Taeg-Kyu, Kang, Keon-Wook, Jeong, Myeong-Seon, Lee, Joo-Eun, Jung, Hyun-Suk, Ro, Hyun-Joo, Jun, Sangmi, Kang, Wonku, Seo, Seung-Yong, Cho, Young-Eun, Song, Byoung-Joon, Baek, Moon-Chang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437193/
https://ncbi.nlm.nih.gov/pubmed/30918259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09387-4
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