Infection by Anaplasma phagocytophilum Requires Recruitment of Low-Density Lipoprotein Cholesterol by Flotillins

Anaplasma phagocytophilum is an obligatory intracellular bacterium that proliferates in membrane-bound inclusions. A. phagocytophilum is dependent on cholesterol and acquire cholesterol from low-density lipoprotein (LDL) endocytosed by mammalian host cells. The mechanism of cholesterol transport to...

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Bibliographic Details
Published in:mBio
Main Authors: Xiong, Qingming, Lin, Mingqun, Huang, Weiyan, Rikihisa, Yasuko
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437059/
https://ncbi.nlm.nih.gov/pubmed/30914515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02783-18
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