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Biocatalytic Hydrogen Atom Transfer: An Invigorating Approach to Free-Radical Reactions

Initiating and terminating free-radical reactions via hydrogen atom transfer (HAT) is an attractive means of avoiding substrate prefunctionalization. Small molecule catalysts and reagents, however, struggle to execute this fundamental step with useful levels of diastereo- and enantioselectivity. In...

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Publicat a:Curr Opin Chem Biol
Autors principals: Nakano, Yuji, Biegasiewicz, Kyle F, Hyster, Todd K
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437003/
https://ncbi.nlm.nih.gov/pubmed/30269010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.09.001
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