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Epigenetic inheritance underlying pulmonary arterial hypertension: a new challenge for network medicine

In pulmonary arterial hypertension (PAH), the Warburg effect (glycolytic shift) and mitochondrial fission are determinants of phenotype alterations characteristic of the disease, such as proliferation, apoptosis resistance, migration, endothelial-mesenchymal transition, and extracellular matrix stif...

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Détails bibliographiques
Publié dans:Arterioscler Thromb Vasc Biol
Auteurs principaux: Napoli, Claudio, Benincasa, Giuditta, Loscalzo, Joseph
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436974/
https://ncbi.nlm.nih.gov/pubmed/30727752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.312262
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