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Epigenetic inheritance underlying pulmonary arterial hypertension: a new challenge for network medicine

In pulmonary arterial hypertension (PAH), the Warburg effect (glycolytic shift) and mitochondrial fission are determinants of phenotype alterations characteristic of the disease, such as proliferation, apoptosis resistance, migration, endothelial-mesenchymal transition, and extracellular matrix stif...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Napoli, Claudio, Benincasa, Giuditta, Loscalzo, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436974/
https://ncbi.nlm.nih.gov/pubmed/30727752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.312262
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