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A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis

Retinoic acid–related orphan receptor α (RORα) is considered a key regulator of polarization in liver macrophages that is closely related to nonalcoholic steatohepatitis (NASH) pathogenesis. However, hepatic microenvironments that support the function of RORα as a polarity regulator were largely unk...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Han, Yong-Hyun, Shin, Kyong-Oh, Kim, Ju-Yeon, Khadka, Daulat B., Kim, Hyeon-Ji, Lee, Yong-Moon, Cho, Won-Jea, Cha, Ji-Young, Lee, Bong-Jin, Lee, Mi-Ock
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436872/
https://ncbi.nlm.nih.gov/pubmed/30855276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124219
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