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Powerful gene set analysis in GWAS with the Generalized Berk-Jones statistic

A common complementary strategy in Genome-Wide Association Studies (GWAS) is to perform Gene Set Analysis (GSA), which tests for the association between one phenotype of interest and an entire set of Single Nucleotide Polymorphisms (SNPs) residing in selected genes. While there exist many tools for...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Sun, Ryan, Hui, Shirley, Bader, Gary D., Lin, Xihong, Kraft, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436759/
https://ncbi.nlm.nih.gov/pubmed/30875371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007530
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