Cooperativity of E-prostanoid receptor subtypes in regulating signaling and growth inhibition in human airway smooth muscle

Prostaglandin E2 (PGE(2)) is produced in the airway during allergic lung inflammation and both promotes and inhibits features of asthma pathology. These mixed effects relate to 4 E-prostanoid (EP) receptor subtypes (EP1, 2, 3 and 4) expressed at different levels on different resident and infiltratin...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Michael, James V., Gavrila, Adelina, Nayak, Ajay P., Pera, Tonio, Liberato, Jennifer R., Polischak, Steven R., Shah, Sushrut D., Deshpande, Deepak A., Penn, Raymond B.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436661/
https://ncbi.nlm.nih.gov/pubmed/30601680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801959R
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